Van de Ven Brace Halts Everton's Run at Brand New Stadium
The Dutch defender emerged as the first defender to net two goals in a English top-flight game for Tottenham since Jan Vertonghen in spring 2013.
Match summary
The Spurs defender nods into the net two times in opening period
The home side's Jake O'Brien has equalizer ruled after VAR review
Senegalese midfielder nets third in 89th minute
The defeat is Everton's first at their new ground
Micky van de Ven found the net twice as Tottenham extended their winning streak on the road in the top division and handed the Toffees their initial loss at their new home.
The Toffees were undefeated in their last five matches at their recently opened stadium at the dockside location, having left Goodison Park behind after more than a century at the end of last season.
But Spurs captain Van de Ven pounced twice from set-pieces in the first half to put their strong form at jeopardy, and they were unable to mount a comeback before Pape Matar Sarr - assisted by ex-Everton forward Richarlison - nodded in a third to put the game to bed.
Jake O'Brien believed he had levelled the tally a short while after the defender's first goal, glancing a bullet header past Guglielmo Vicario from an Everton corner.
Beto, meanwhile, failed to convert a handful of opportunities, while Vicario made a succession of fine saves to ensure the London club went five away games without defeat in the English top flight.
But the VAR intervened, instructing Craig Pawson to check the score on the screen and the official ruled that the winger and the attacker were in offside positions and had impeded with the Spurs keeper.
This victory moves the manager's team into third place in the division, a handful of points off local foes and leaders the Gunners.
The Merseyside club stay in 14th position and sit six points clear of the relegation zone.
Spurs breakdown: The defender excels in duties at both ends of the field
After a uninspiring weekday performance in the European competition against the French side, where they managed a only two shots on target, Frank opted for Randal Kolo Muani up front instead of ex-Everton forward the Brazilian.
The summer signing was failed to influence the game before being substituted for the substitute after 60 minutes on the field, but it emerged he proved unnecessary in the end.
Defender Van de Ven converted into an attacking force to be feared.
Spurs' first goal came from a cleverly executed set-piece play, with Rodrigo Bentancur heading the ball toward the face of goal for an free the defender to head home.
And the captain - stepping up as skipper in Cristian Romero's unavailability - notched his second in added time as he rose above the England keeper to nod in.
Van de Ven was just as outstanding in defensive duties, combining well with his defensive colleague as the pair dealt superbly with the numerous deliveries sent their way by the opposition.
Everton analysis: Everton lacking striker's instinct
Everton's recent stadium had been a fortress, but it seems the freshness may have worn off slightly and supporters headed to the exits after Sarr's final goal for Spurs.
The break in the team's unbeaten home run will not be a major worry for David Moyes, but their striker situation are.
Beto and the other striker - the Everton's pair of recognised centre-forwards - had scored just a single goal combined before the weekend's outing.
And they were failed to contribute to that miserable record on a damp and dreary evening on Merseyside.
Beto's form was epitomized when he chose to overhead kick a golden opportunity from close range, despite having room and time to reposition for a more conventional attempt that would have tested the keeper.
Barry, as well, failed to influence the game after replacing Beto in the second half.
It wasn't for a lack of opportunity. The majority of the home side's offensive moves came through the winger and Ndiaye, who relentlessly delivered dangerous balls into the Spurs box.
Upcoming fixtures for these two sides?
The Toffees: The team head to Sunderland in the Premier League on Monday, 3 November at 8 PM.
Spurs: Spurs travel to St James' Park on Wednesday, 29 October for their next round League Cup match against Newcastle.